SERODIA® - TP-PA
Syphilis IgG EIA
Specimen Collection Instructions
Blood should be collected in a plastic, sterile STD Program approved collection tube. Please follow the manufacturer's instructions on clot time and centrifuge speed/time requirements.
The Syphilis Serology Lab 16 form must be filled out completely. The following information must be included on the form:
Storage and Transport Instructions
Speciments should be shipped refrigerated (2-8ºC). Specimens can be stored for up to 5 days at 2-8ºC. For longer storage, specimens must be frozen at -20ºC or colder. Frozen specimens must be shipped on dry ice and received at a temperature of -20ºC or colder. Sera may be frozen and thawed only once.
Causes for Rejection
Limitations for the Procedure
The Serodia® TP-PA test is specific for detecting Treponema pallidum antibodies in serum. It does not detect T. pallidum directly. As will all serological tests for syphilis, interpretation of results obtained with this test must be used in conjunction with the patient's clinical sypmtoms, medical history and other clinical and/or laboratory findings to produce an overall clinical diagnosis. All treponemal tests tend to remain reactive following treponemal infection; therefore, they should not be used to evaluate response to therapy. This test may be reactive in a small percentage (less than 1%) of normal or healthy persons; these false-positive results are often transient, their cause unknown. False positive results may occur in association with other underlying illnesses and may be reactive in persons from areas where yaws or pinta was, or is, endemic. Samples from patients with HIV, Leprosy, Toxoplasmosis, H. pylori, or drug addiction may react, on occasion, with either the sensitized or the unsensitized particles, causing false-positive or Inconclusive results.